Your browser does not support JavaScript!
藥學暨健康學院介紹
院長簡介

謝博銓 教授兼藥學暨健康學院院長

 

   

學歷:

  1. 國立中山大學,化學研究所,博士
  2. 星藥科大學,大學院,碩士

經歷:

  1. 大仁技術學院藥學系,講師,1990-08-01~2001-07-31
  2. 大仁技術學院藥學系暨製藥所,副教授,2001-08-01~ 2010-06-30
  3. 大仁技術學院研究發展處,組長,2001-08-01~ 2003-07-31
  4. 大仁科技大學研究發展處,2003-08-01~ 2009-02-28
  5. 大仁科技大學藥學系暨製藥所主任兼所長,2010-08-01~ 2015-08-31
  6. 大仁科技大學藥學系(所) ,教授,2010-07-01~
  7. 大仁科技大學藥學系(所)主任2018-02~
  8. 大仁科技大學藥學暨健康學院院長2018-02~

專長:有機合成、藥物合成

 

 Journal Papers

  1.  Pochuan Shiehf,Kaempferol inhibits angiogenesis ability through targeting VEGF receptor-2 and down-regulating,Oncology Reports (2018)
  2. He-Hsiung Chenga,1, Chiang-Ting Choub,c, Wei-Zhe Liangd,1, Chun-Chi Kuoe, Pochuan Shiehf,⁎,Jue-Long Wangg,⁎, Chung-Ren Jand,⁎,Effects of puerarin on intracellular Ca2+ and cell viability of MDCK renaltubular cellsEnvironmental  Toxicology and Pharmacology,52(2017)83-89
  3. Pochuan Shiehf,*,Effect of Protriptyline on [Ca2+]i and Viability in MDCK Renal Tubular Cells ,The Chinese Journal of Physiology中國生理學雜誌 ,60(2017)
  4. Min-Huan Wua,b, Ting-Hsuan Leec, Hsiang-Ping Leed,e, Te-Mao Lid, I-Tee Leee,f,g,Po-Chuen Shiehc,*, Chih-Hsin Tangi,j,k* Kuei-Lu-Er-Xian-Jiao extract enhances BMP-2 production in osteoblasts,Original article,March 2017, Vol. 7, No. 1
  5. Jeng-Hsien Yeh1, 2, Chiang-Ting Chou3, 4, I-Shu Chen5, Ti Lu6, Ko-Long Lin7,
    Chia-Cheng Yu5, Wei-Zhe Liang8, Hong-Tai Chang5, Chun-Chi Kuo9, Chin-Man Ho8,Wen-Teng Chang2, Pochuen Shieh10, and Chung-Ren Jan8 ,Effect of Thymol on Ca2+ Homeostasis andViability in PC3 Human Prostate Cancer Cells, Chinese Journal of Physiology 60(1): 32-40, 2017
  6. Jue-Long Wang, Chiang-Ting Chou, Wei-Zhe Liang, Jeng-Hsien Yeh, Chun-Chi
    Kuo, Chao-Ying Lee, Pochuen Shieh, Daih-Huang Kuo, Fu-An Chen & Chung-Ren Jan,Effect of 2,5-dimethylphenol on Ca2+ movement and viability in PC3 human prostate cancer cells,Toxicology Mechanisms and Methods,07 July 2016
  7. He-Hsiung Cheng1, #, Chiang-Ting Chou2, 3, #, Wei-Zhe Liang4, Jin-Shiung Cheng5, Hong-Tai Chang6, Chun-Chi Kuo7, I-S Chen6, Ti Lu8, C-C Yu6, Fu-An Chen9, Daih-Huang Kuo9,Pochuen Shieh9, and Chung-Ren Jan4,Effect of NPC15199 on [Ca2+]i and Viability inSCM1 Human Gastric Cancer Cells,Chinese Journal of Physiology 59(5): 268-275, 2016
  8. Hong-Tai Chang, Chiang-Ting Chou, You-Sheng Lin, Pochuen Shieh, Daih-Huang Kuo, Chung-Ren Jan, Wei-Zhe Liang (2016, Apr). Esculetin, a natural coumarin compound, evokes Ca2+ movement and activation of Ca2+-associated mitochondrial apoptotic pathways that involved cell cycle arrest in ZR-75-1 human breast cancer cells. Tumor Biol, 37:4665–4678.
  9. Cherng-Jau Roan, Chiang-Ting Chou, Wei-Zhe Liang,Hong-Tai Chang,Daih-Huang Kuo, Chun-Chi Kuo, Fu-An Chen, Pochuen Shieh, and Chung-Ren Jan (2015, Dec). Effect of Miconazole on [Ca2+]i and Cytotoxicity in ZR-75-1 Human Breast Cancer Cells. Chinese Journal of Physiology, 58(6),377-384.
  10. Kuan-Yun Chen, Chih-Yang Lin, Chun-Jun Yang, Sen Yang, Po-Chuen Shieh, and Chih-Hsin Tang (2015, Dec). Effects of WISP-1 on Matrix Metalloproteinase Expression and Wound Healing in Human Skin Fibroblasts via Down-Regulation of miR-519d. Adaptive Medicine, 7(4),202-209.
  11. Tzu-Yi Hung, Chiang-Ting Chou, Te-Kung Sun, Wei-Zhe Liang,Jin-Shiung Cheng, Yi-Chien Fang, Yih-Do Li, Pochuen Shieh, Chin-Man Ho,Chun-Chi Kuo, Jia-Rong Lin, Daih-Huang Kuo, and Chung-Ren Jan (2015, Oct). The Mechanism of Safrole-Induced [Ca2+]i Rises and Non-Ca2+-Triggered Cell Death in SCM1 Human Gastric Cancer Cells. Chinese Journal of Physiology, 58(5),302-311.
  12. Yih-Do Li, Chiang-Ting Chou, Wei-Zhe Liang, Hui-Wen Tseng, Yi-Chien Fang,Tzu-Yi Hung, Hong-Tai Chang,Daih-Huang Kuo, Chun-Chi Kuo, Chin-Man Ho,Pochuen Shieh, Fu-An Chen, and Chung-Ren Jan (2015, Oct). Effect of NPC-14686(Fmoc-l-Homophenylalanine) on Ca2+ Homeostasis and Viability in OC2 Human Oral Cancer Cells. Chinese Journal of Physiology, 58(5), 285-293.
  13. Jau-Min Chien, Chiang-Ting Chou, Wei-Zhe Liang, Daih-Huang Kuo, Chin-man Ho, Pochuen Shieh and Chung-Ren Jan (2015, Jul). Effect of Antidepressant Doxepin on Ca²⁺ Homeostasis and Viability in PC3 Human Prostate Cancer Cells. , 30;58(3):178-87.
  14. Chi-Ting Horng ,Chiang-Ting Chou ,Hui-Wen Tseng ,Jin-Shiung Cheng ,Hong-Tai Chang ,Po-Min Chang ,I-Li Chen ,Ming-Chi Hung ,Yi-Jen Tsai ,Peng-Chih Tsai ,Wei-Zhe Liang ,Chun-Chi Kuo ,Daih-Huang Kuo ,Chin-Man Ho ,Jia-Rong Lin ,Pochuen Shieh* and Chung-Ren Jan*. (2015, Feb). Effect of methoxychlor on ca2 homeostasis and apoptosis in HA59T Human Hepatoma Cells.. Chinese Journal of Physiology., 28;58(1):1-8.. (Accepted).
  15. Jue-Long Wang1,*,Chiang-Ting Chou2,3,*,Te-Kung Sun4,Wei-Zhe Liang5,Jin-Shiung Cheng6,Chia-Hheng Yu7,Hong-Tai Chang7,Hui-Wen Tseng8,Chun-Chi Kuo9,Fu-An Chen10,Daih-Huang Kuo10,Pochuen Shieh10,and Chung-Ren Jan5 (2014, Nov). Capsazepine-Induced Ca2+ Signaling in HA59T Human Hepatoma Cells. Adaptive Medicine, 6(4):161-167.
  16. Wei-Zhe Liang , Chiang-Ting Chou , Hong-Tai Chang , Jin-Shiung Cheng , Daih-Huang Kuo , Kuang-Chung Ko , Ni-Na Chiang , Ru-Fang Wu , Pochuen Shieh , Chung-Ren Jan * (2014, Jul). The mechanism of honokiol-induced intracellular Ca2+ rises and apoptosis in human glioblastoma cells. . Chemico-Biological Interactions, 221 (2014) 13–23.
  17. Chi-Ting Horng , Po-Chuen Shieh , Tzu-Wei Tan , Wei-Hung Yang and Chih-Hsin Tang * (2014, Jun). Paeonol Suppresses Chondrosarcoma Metastasis through Up-Regulation of miR-141 by Modulating PKCδ and c-Src Signaling Pathway.. International Journal of Molecular Sciences, 15, 11760-11772. (Accepted).
  18. Chi-Ting Horng1,#,Chiang-Ting Chou2,3,#,Hui-Wen Tseng4,Jin-Shiung Cheng5,Hong-Tai Chang6,Po-Min Chang6,I-Li Chen7,Ming-Chi Hung7,Yi-Jen Tsai7,Peng-Chih Tsai7,Wei-Zhe Liang8,Chun-Chi Kuo9,Daih-Huang Kuo7,Chin-Man Ho8,Jia-Rong Lin8,Pochuen Shieh7,* and Chung-Ren Jan8,* (2014, May). Effect of Methoxychlor Ca²⁺ Homeostasis and Apoptosis in HA59T Human Hepatoma Cells . Chinese Journal of Physiology, 58(1):1-8.
  19. Jin Shiung Cheng *, Chiang-Ting Chou *, Wei-Zhe Liang , Chun-Chi Kuo , Pochuen Shieh , Daih-Huang Kuo , and Chung-Ren Jan. (2014, Apr). The mechanism of bifonazole-induced [Ca2+]i rises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells.. Journal of Receptors and Signal Transduction, 34(6): 493–499..
  20. Chang HT1, Chen IL, Chou CT, Liang WZ, Kuo DH, Shieh P, Jan CR. (2013, Dec). Effect of caffeic acid on Ca2+ homeostasis and apoptosis in SCM1 human gastric cancer cells . Arch Toxicol, 87(12):2141-50.
  21. Jau-Min Chien , Chiang-Ting Chou , Wei-Zhe Liang , Daih-Huang Kuo , Chun-Chi Kuo , Chin-Man Ho , Pochuen Shieh , and Chung-Ren Jan . (2013, Oct). The Mechanism of NPC-14686-Induced [Ca2+]i Rises and Non-Ca2+-Triggered Cell Death in MG63 Human Osteosarcoma Cells.. Chinese Journal of Physiology, 57(3): 158-166, 2014..
  22. Liu CP1, Chou CT, Liang WZ, Cheng JS, Chang HT, Kuo DH, Ko KC, Chiang NN, Wu RF, Shieh P, Jan CR. (2013, Jun). Pathways of [Ca2+]i rise evoked by angiotensin II in MDCK renal tubular cells . J Recept Signal Transduct Res, 33(6):380-6.
  23. Chang HT1, Chou CT, Chen IL, Liang WZ, Kuo DH, Huang JK, Shieh P, Jan CR. (2013, May). Mechanisms of resveratrol-induced changes in [Ca2t]i and cell viability in PC3 human prostate cancer cells . J Recept Signal Transduct Res, 33(5):298-303.
  24. Horng CT1, Chiang NN, Chen IL, Liang WZ, Chen IS, Kuo DH, Shieh PC, Jan CR. (2013, Feb). Effect of clotrimazole on cytosolic Ca2+ rise and viability in HA59T . J Recept Signal Transduct Res, 33(2):89-95.
  25. Agoramoorthy G, Shieh P, Horng CT. (2012, Mar). Elderly and impoverished cancer patients need urgent help in India. Rev Med Chil, 140(4):546-7.
  26. 謝博銓(20121)花草精靈-精油的奧秘科學發展月刊
  27. 謝博銓(20121)花草精靈-天然精油的抽提工藝科學發展月刊
  28. Wei-Chuan Liao,Chiang-Ting Chou,Chun-Chi Kuo,Chih-Chuan Pan,Daih-Huang KUO,Pochuen Shieh,Jin-Shiung Cheng,Chung-Ren Jan,and Chen-Fu Shaw(20111) Effect of Thimerosal on Ca2+ Movement and Apoptosis in PC3 Prostate Cancer Cells,DRUG DEVELOPMENT RESEARCH(SCI)
  29. Ming-Ling Tsai, Chi-Ting Horng, Chung-Cheng Liu, MD, Pochuen Shieh, Chwen-Ling Hung,Da-Wen Lu, Shang-Yi Chiang, Yi-Cheng Wu, and Wen-Yaw Chiou(20111) Ocular Responses and Visual Performance after Emergent Acceleration Stress, Physiology and Pharmacology(SCI)
  30. Chen JJ, Lin WJ, Shieh PC, Chen IS, Peng CF, Sung PJ.(20095)A New Long-Chain Alkene and Antituberculosis Constituents from the Leaves of Pourthiaea lucida,Verlag Helvetica Chimica Acta 469 2012.01(SCI)

 

 

 TOP

Conference Papers

  1. Mei-Chun Ting (丁美純)1, Hui-Hsiang Chang(張惠香)2, Chia-Hsin Chang (張家馨)1, Po-Chuen Shieh (謝博銓)1*(2013/1/22)Effects of blue shark cartilage alkaline extract on cytokine secretions in bronchoalveolar lavage fluid of ovalbumin-sensitized and –challenged mice 2013台灣藥學會藥物化學研討會,台灣
  2. Fang-Yu Tu (杜仿裕)1, Hui-Hsiang Chang (張惠香)2, Ting-Hsi Chang (張庭溪)1,Po-Chuen Shieh (謝博銓)1*(2013/1/22)Anti-inflammatory effects of the extracts from Hylocereus polyrhizus fruit peel on primary peritoneal cells from BABL/c mice 2013台灣藥學會藥物化學研討會,台灣
  3. Hui Wen Liang 1, I-Li Chen1, Daih-Huang Kuo1, Po-Chuen Shieh1*(2013/1/22)Comparison of Various Extraction Methods for the 5,6-dehydrokawain(DK) Determination and Bioctivities of Alpinia zerumbet collected from Pingtung County2013台灣藥學會藥物化學研討會,台灣
  4. Chuan-Jhao Jhuang1, Yu-Wen Liao2, Po-Chuen Shieh1*(2013/1/22)Comparison of Various Extraction Methods for the Evaluation of Bioactivities of Vitex negundo collected from the lowland subtropical habitat in southern Taiwan,2013台灣藥學會藥物化學研討會,台灣
  5. Horng CT, Chiang NN, Chen IL, Liang WZ, Chen IS, Kuo DH, Shieh PC, Jan CR.(2013/1/22)Effect of clotrimazole on cytosolic Ca2+ rise and viability in HA59T human hepatoma cells,2013台灣藥學會藥物化學研討會,台灣
  6. Fang-Yu Tu (杜仿裕)1, Hui-Hsiang Chang (張惠香)2, Ting-Hsi Chang (張庭溪)1,Po-Chuen Shieh (謝博銓)1*(2012/10/6) Anti-inflammatory effects of the extracts from Hylocereus polyrhizus fruit peel on primary peritoneal cells from BABL/c mice,27屆天然藥物研討會,台灣
  7. Po-Chuen ShiehHui-Hsiang ChangFa ng-Yu Tu(2012/8/25)Anti-inflammatory effects of the extracts from Hylocereus polyrhizus fruit peel on primary peritoneal cells from BABL/c mice第八屆世界華人藥物化學研討會暨第九屆IUPAC化學生物學研討會,大陸
  8. Mei-Chun Ting (丁美純)1, Hui-Hsiang Chang(張惠香)2, Chia-Hsin Chang (張家馨)1, Po-Chuen Shieh (謝博銓)1*(2012/8/25)Effects of blue shark cartilage alkaline extract on cytokine secretions in bronchoalveolar lavage fluid of ovalbumin-sensitized and -challenged mice,第八屆世界華人藥物化學研討會暨第九屆IUPAC化學生物學研討會,大陸
  9. Chun-Mao Cheng (鄭君茂), Hui-Hsiang Chang (張惠香), Po-Chung Shien (謝博銓) (2011/12/3)Effect of 50% alcohol of purple sweet potato leaf on cytokine secretions in Bronchiolar lavage fluid of ovalbumin-sensitized and-challenged mice,一百年度台灣藥學會年會暨學術研討會,台灣
  10. Ying-Tang Chang (張盈棠), Hui-Hsiang Chang (張惠香), Po-Chung Shien (謝博銓) (2011/12/3)Effect of 50% alcohol of purple sweet potato leaf on the levels of serum antibodies of ovalbumin-sensitzed and-challenged mice,一百年度台灣藥學會年會暨學術研討會,台灣
  11. Po-Chuen Shieh*, Chin-Hung Lee,Ng Ling Yi, Chung-Ren Jan (2009/6/28)Carvedilol-induced Elevation in Cytosolic Free Ca2+ Level and Apoptosis in SIRC Corneal Epithelial Cells,2009台灣藥學會藥物化學研討會,台灣
  12. 李秋芳、傅文正、郭代璜、謝博銓、戴秀華、黎淑雲、陳福安* (2009/6/28)Effects of Different Modes of Exercise on Pharmacokinetics of Ferulic acid,2009台灣藥學會藥物化學研討會,台灣
  13. G. Agoramoorthy, F.A Chen, V.Venkatesalu and Po-Chuen Shieh*.(2009/5/2)Bioconcentration of heavy metals in selected medicinal plants of India天然藥物研討會,台灣
  14. Po-Chuen Shieh, Govindasamy Agoramoorthy and Daih-Huang Kuo (2009/5/2)Evaluation of Antioxidant Polyphenols in Taiwan's Medicinal Plants 天然藥物研討會,台灣
  15. GOVINDASAMY AGORAMOORTHY,FU-AN CHEN,VENUGOPALAN VENKATESALUT,DAIH-HUANG KUO and PO-CHUEN SHEA*(2009/5/2) Evaluation of Antioxidant Polyphenols from Selected Mangrove Plants of India 天然藥物研討會,台灣
  16. Shin-Wen Tsai, Tzy-Ming Lu, Cuei-Fong Jhuang, Shin-Chin Ng, Fu-An Chen, Po-Chuen Shieh, Ming-Chi Hung, Daih-Huang Kuo*(2009/11/28)Vasorelaxation Effect and Antioxidant activity of the Isoflavone in Isolated Porcine Coronary arteries,98年度台灣藥學會年會,台灣
  17. Shin-Wen Tsai, Tzy-Ming Lu, Cuei-Fong Jhuang, Shin-Chin Ng, Fu-An Chen, Po-Chuen Shieh, Ming-Chi Hung, Daih-Huang Kuo*. Vasorelaxation Effect aond Antioxidant activity of Isoflavone in Isolated Porcine Coronary arteries. (2009) 台灣藥學會暨社區藥局實習教學國際研討會,20091128日,151-2頁。(臺北醫學大學)
  18. Shieh PC, Tsai ML, Chiu MH, Chen YO, Yi NL, Jan CR.(2009/11/28)Independent Effects of the Broccoli-derived Compound Sulforaphane on Ca2+ Influx and Apoptosis in Madin-Darby Canine Renal Tubular Cells,98年度台灣藥學會年會,台灣
  19. 謝博銓、鄭淑分、陳福安、黎淑雲、李春燕、劉立敏、陳信維、洪啟庭、郭代璜* (2008/4/25)The Study of Taiwan Traditional Medicinal Plants on Hyperuricemia,2008台灣藥學會藥物化學研討會,台灣
  20. 謝博銓、陳福安、劉立敏、李治宏、傅文正、蔡雅文、郭代璜,(2007/12/8)Pharmacokinetic Study of Lutein in rats,台灣藥學會年會暨學術研討會,台灣
  21. Po-Chuen Shieh.(2007/5/18)Study of synthesis and structure-activity relationship of 4-hydroxychalcone derivatives,2007台灣藥學會藥物化學研討會,台灣
  22. 陳日榮,林文就,謝博銓,丁家崴,羅雅欣,張晉銘,尤迎如 (2006/12/23)Novel benzenoid and 1,3-dioxolan-2-one derivatives from fruiting body of Antrodia cinnamonea,九十五年度台灣藥學會年會暨學術研討會,台灣
  23. 洪啟庭,施承典,陳福安,謝博銓,古煜華,康文馨,蔡雅文,郭代璜* (2006/12/23)Cardiovasular effects of Rhodiola rosea.台灣藥學會年會暨學術研討會,台灣
  24. Fu-An Chen, Po-Chuen Shieh, Shih-Yu Hsiang, Wen-Jeng Fu, Yu-Hua Gu, Chih-Ping Chang, Daih-Huang Kuo (2006/12/23)The Effect of Burdock on Gastrointestinal Function of Rat 2006 台灣藥學會年會暨學術研討會 台灣
  25. Pochuen Shieh, Ya-Ping Tang(2005/9/4)Synthesis and Structure-Activity Relationships of Oxazolidines and Oxazolidinones,2005年藥物化學研討會,台灣
  26. KUO Daih-Huang ; SHIEH Pochuen ; YANG Bin-Hong ; HORNG Chi-Ting ; CHEN Fu-An ;(2004/12/18)Studies of n-Hexene Extract of Cymbopogon Citratus on Porcine Coronary Artery,中國藥學會年會暨藥學及藥學教育研討會,台灣
  27. 謝博銓a、鄭可大b、廖長輝c、湯雅評a、黃良得d(2004/3/5)台灣山苦瓜(Momordica dioica)之基源鑑定分析及抗氧化與自由基清除活性評估,2004藥物化學研討會暨慶祝高雄醫學大學,台灣

 

 TOP

Patent

  1. 發明人:郭代璜,謝博銓,陳福安設置有精油揮發效應的涼風扇,發明第M452810號,中華民國專利2013.5.11-2022.11.22
  2. 發明人:郭代璜,謝博銓,陳福安設置在筆具上的防蟲液噴灑裝置,發明第M450993號,中華民國專利2013.4.21-2022.11.22
  3. 發明人 :郭代璜,謝博銓,陳福安,洪明吉設置有防蟲液噴灑裝置的手電筒,發明第M450992號,中華民國專利2013.4.21-2022.11.22
  4. 發明人:謝博銓可裝置香精膏之飾品,發明第M399627號,中華民國專利2011.3.11-2020.10.4
  5. 發明人:謝博銓,吳天賞,郭代璜,陳福安,黃秀琴精油萃取裝置,發明第M408403號,中華民國專利2011.8.1-2020.9.29
  6. 發明人:謝博銓,吳天賞,郭代璜,陳福安,黃秀琴高效率植物精油萃取裝置,發明第M371579號,中華民國專利2010.1.1-2019.6.22

 

Books

  • 謝博銓“科學發展月刊”,行政院國家科學委員會,熱帶植物精油相關產品之研發三年計畫,2012年1月出版